Acta Photonica Sinica ›› 2019, Vol. 48 ›› Issue (4): 416002-0416002.doi: 10.3788/gzxb20194804.0416002

• Materials • Previous Articles     Next Articles

Effects of Iron Ions on the Interaction of CS-Fe3O4@ZnS:Mn/ZnS Magnetic-fluorescent Nanoparticles with Bovine Serum Albumin by Molecular Spectroscopy

PENG Mao-min, XIA Hong, LIU Li   

  1. Institute of Quality Standard & Testing Technology for Agro-Products, Hubei Academy of Agricultural Sciences, Wuhan 430064, China
  • Received:2018-12-02 Online:2019-04-25 Published:2019-01-23
  • Contact: 2019-01-23
  • Supported by:

    Key Laboratory of Agrifood Safety and Quality,Ministry of Agriculture of China (No.2018-KF-09),Natural Science Foundation of Hubei Province of China (No.2016CFB213),Hubei Academy of Agricultural Sciences Youth Talent Training Program (No.Q2018034),Youth Science Foundation of Hubei Academy of Agricultural Science (No.2015NKYJJ15)

Abstract:

The effects of Fe3+ or Fe2+ ions on the interaction of CS-Fe3O4@ZnS:Mn/ZnS Magnetic-Fluorescent Nanoparticles (MFNPs) with Bovine Serum Albumin (BSA) have been studied using UV-visible and fluorescence spectroscopy.It was found that both the fluorescence intensity of CS-Fe3O4@ZnS:Mn/ZnS MFNPs and BSA became weakened when Fe3+ or Fe2+ concentrations reached their physiological levels.Meanwhile,the interaction of CS-Fe3O4@ZnS:Mn/ZnS MFNPs with BSA in the presence of Fe3+ or Fe2+ enhanced.There is synergic effect of CS-Fe3O4@ZnS:Mn/ZnS MFNPs and Fe3+ or Fe2+ on the damage of BSA.These results are important for understanding the influence of different biological environments on interaction between MFNPs and proteins.

Key words: Bovine serum albumin, Fluorescence quenching, Interaction, Magnetic-fluorescent nanoparticles, Iron ions

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