Acta Photonica Sinica ›› 2019, Vol. 48 ›› Issue (4): 416002-0416002.doi: 10.3788/gzxb20194804.0416002

• Materials • Previous Articles     Next Articles

Effects of Iron Ions on the Interaction of CS-Fe3O4@ZnS:Mn/ZnS Magnetic-fluorescent Nanoparticles with Bovine Serum Albumin by Molecular Spectroscopy

PENG Mao-min, XIA Hong, LIU Li   

  1. Institute of Quality Standard & Testing Technology for Agro-Products, Hubei Academy of Agricultural Sciences, Wuhan 430064, China
  • Received:2018-12-02 Online:2019-04-25 Published:2019-01-23
  • Contact: 2019-01-23
  • Supported by:

    Key Laboratory of Agrifood Safety and Quality,Ministry of Agriculture of China (No.2018-KF-09),Natural Science Foundation of Hubei Province of China (No.2016CFB213),Hubei Academy of Agricultural Sciences Youth Talent Training Program (No.Q2018034),Youth Science Foundation of Hubei Academy of Agricultural Science (No.2015NKYJJ15)


The effects of Fe3+ or Fe2+ ions on the interaction of CS-Fe3O4@ZnS:Mn/ZnS Magnetic-Fluorescent Nanoparticles (MFNPs) with Bovine Serum Albumin (BSA) have been studied using UV-visible and fluorescence spectroscopy.It was found that both the fluorescence intensity of CS-Fe3O4@ZnS:Mn/ZnS MFNPs and BSA became weakened when Fe3+ or Fe2+ concentrations reached their physiological levels.Meanwhile,the interaction of CS-Fe3O4@ZnS:Mn/ZnS MFNPs with BSA in the presence of Fe3+ or Fe2+ enhanced.There is synergic effect of CS-Fe3O4@ZnS:Mn/ZnS MFNPs and Fe3+ or Fe2+ on the damage of BSA.These results are important for understanding the influence of different biological environments on interaction between MFNPs and proteins.

Key words: Bovine serum albumin, Fluorescence quenching, Interaction, Magnetic-fluorescent nanoparticles, Iron ions

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